World-class care for advanced prostate cancer begins here.
At Mayo Clinic Comprehensive Cancer Center, you’ll get a precise diagnosis and the latest treatment options provided by the world’s most experienced advanced prostate cancer experts. Here, you are at the center of a team that truly advocates for you at the No. 1 hospital for cancer in the Midwest.
- Appointments as soon as two days, instead of two weeks. Mayo Clinic in Rochester, Minnesota, is committed to seeing you as soon as possible, so you have confidence in your care plan and the journey ahead faster.
- Improved quality of life. Our teams work with you to understand your goals during and after treatment. You’ll have access to the latest treatments, including prostate-specific membrane antigen (PSMA) targeted therapy, that minimizes side effects so you can live your best possible life.
- Treatment advancements not available elsewhere. Our physician scientists are leaders in developing new treatment options providing hope through clinical trials not available elsewhere.
We offer hope for advanced prostate cancer, when others can’t.
Mayo Clinic’s depth of expertise and access to the latest technology allows us to better treat advanced prostate cancer, also called metastatic prostate cancer. More than 28,000 people with prostate cancer come to Mayo Clinic each year seeking the right answers.
Getting a second or third opinion for advanced prostate cancer at Mayo Clinic is about finding options, hope and the best possible outcome for you.
The Mayo Clinic Difference
Advanced Prostate Cancer Care at Mayo Clinic
Radiopharmaceuticals for Advanced Prostate Cancer
The power of advanced diagnostics.
When treating cancer, seeing is everything. If there is risk your prostate cancer will or has spread to other parts of your body, Mayo Clinic experts use PSMA-PET scan to better find your cancer. This full-body molecular scan allows your care team to see precisely where the cancer is, if it has spread and if your treatment is working. The scan uses a special dye with radioactive tracers that illuminate hard-to-find cancer cells so your cancer can be found earlier, and your therapy can be adjusted based on each individual tumors' response to treatment.
Life-prolonging therapies designed to minimize side effects.
- PSMA-targeted therapy is now available for even more people with PSMA+ metastatic castrate-resistant prostate cancer. A radiopharmaceutical, lutetium LU 177 vipivotide tetraxetan targets and sticks to cancer cells to precisely deliver treatment. Mayo Clinic experts have been involved with developing this therapy and have more experience with itthis therapy than any other center in the world. In March 2025, the FDA approved this therapy to be used after
one androgen receptor pathway inhibitor (ARPI) and now before chemotherapy, tripling the number of people eligible.
- Hormone therapy can cut off the supply of testosterone to cancer cells causing them to die or grow more slowly.
- PARP Inhibitors are a type of targeted therapy that attacks cancer cells, causing them to die. In metastatic prostate cancer, these medicines might be used when hormone therapy is no longer working.
- Chemotherapy is sometimes used with hormone therapy or could also help treat advanced prostate cancer when hormone therapy isn’t working.
- Stereotactic body radiation therapy uses high doses of radiation aimed at different angles to precisely target the tumor and limit radiation exposure to healthy tissue and can be used to address sites of cancer spread.
Powerful innovation through clinical trials.
Mayo Clinic physicians conduct research to bring advancements to patients faster. We are continuously working to develop the next great advancements for even the most advanced prostate cancers. You can find the most promising prostate cancer clinical trials at Mayo Clinic today.
Nationally recognized for expertise.
Mayo Clinic was one of the National Cancer Institute’s first designated comprehensive cancer centers, proudly recognized for our scientific leadership and resources. Mayo Clinic in Rochester, Minnesota, is ranked among the top hospitals in the nation for urology and for cancer by U.S. News & World Report.
One of the National Cancer Institute’s first Designated Comprehensive Cancer Centers.
Proudly recognized for our scientific leadership and resources, providing state-of-the-art care today while developing the care of tomorrow.
The highest standard of care, highly accessible.
We accept most insurance plans, so the greatest number of people possible can receive the care they deserve.
Your peace of mind is worth the trip.
If you need to travel to Mayo Clinic for care, getting here from anywhere is easier than ever. Our dedicated travel coordination team will handle all the details, so you can stay focused on your health. We offer custom trip-planning services when you book with Patient Travel Services.
We can help:
- Change your flight if your appointments change.
- Arrange hotel accommodation close to the Mayo Clinic campus.
- Book ground transportation to help you get around.
- Request special accommodations based upon your health condition or needs.
Get in touch today and we’ll get your itinerary started. Our agents can help you plan and tailor your trip to your needs. They’re available Monday through Friday, 8:30 a.m. to 5:30 p.m., Central Time.
Contact us to request an appointment.
Rochester, MN
200 First St. SW,
Rochester, MN 55905
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