Phoenix, AZ

8 a.m. to 5 p.m. Mountain Time

World-Class Care for Brain Cancer Begins Here

At Mayo Clinic, we continue to innovate so you can focus on life beyond brain cancer. We bring together a team of experts specialized in your individual tumor type who create an individualized care plan for your needs – one that includes all aspects of treatment, recovery, and quality of life.

  • Reduced hospital stays. Many people who undergo brain tumor surgery at Mayo Clinic leave the hospital in one or two days.
  • Lower complication rates. Technological advances allow our surgeons and radiation oncologists to avoid injury to healthy brain tissue.
  • Shorter recovery time. Minimally invasive procedures often result in smaller incisions and scars.
  • Improved quality of life. We manage side effects and work to preserve and maintain motor and cognitive function, speech, cosmetic outcomes, and psychological well-being. 

We operate on tumors that other centers may not.

With our expertise and technology, we often treat people with Stage 3 or 4, or metastatic brain cancer. More than 7,000 adults and children with brain and other central nervous system cancers come to Mayo Clinic each year.


Getting a second or third opinion at Mayo Clinic for an advanced or “inoperable” tumor is about finding options and the best possible outcome for you.

Surgical innovations for safer procedures.

We use advanced technologies to operate closer to vital areas of the brain with confidence and make procedures safer.

  • 3-D printing, augmented reality, and holography to plan the least invasive approach to surgery.
  • Intraoperative MRI (iMRI) to map the brain and maintain functional areas.
  • Awake brain surgery, also known as an awake craniotomy, allows the Mayo Clinic surgical team to ask questions of the patient and monitor activity in the brain during the responses. This back-and-forth helps ensure the surgery to remove a tumor isn't affecting the patient's communication and cognition skills.
  • Fluorescence-guided surgery to visualize the tumor’s location more precisely.
  • Minimally invasive, scarless brain surgery to enable faster recovery with fewer side effects. Approaches include key-hole surgery, radiosurgery, laser thermal ablation, and proton beam radiotherapy.  

The power of advanced diagnostics.

We analyze the tumor and your healthy brain tissue using advanced approaches, so we can make treatment decisions that are more precise and personalized for you.

  • Molecular diagnostics to analyze your tumor’s DNA and predict which treatments will work best for your specific tumor type.
  • Functional and metabolic activity analysis to learn about tumor metabolism and functioning of the surrounding area.
  • 7 – Tesla MRI - This imaging system uses a stronger magnetic field to produce more detailed images of the body's interior. Detailed brain scans help Mayo Clinic care teams diagnose and treat patients with brain tumors. This advanced imaging technology is key to ensuring patients receive an accurate diagnosis to guide treatment.
  • Tumor firmness and adhesion analysis to determine the tumor’s firmness and adhesion to healthy brain tissue, so your surgical team can plan with precision. This state-of-the art technology was invented at Mayo Clinic.  

Therapies designed to minimize side effects.

Our radiation therapies are designed to target tumor cells and minimize effects on healthy brain tissue.

  • Stereotactic radiosurgery includes Gamma Knife®, which delivers a high dose of radiation to a very small area of the brain.
  • Proton beam therapy delivers precise radiotherapy to the tumor with less radiation to the surrounding brain tissue.

Innovative treatments and clinical trials.

Our physicians conduct research to bring advancement to patients faster with treatments and clinical trials. You can find the latest brain tumor clinical trials at Mayo Clinic.

Research includes:

  • The most effective combination of medications and radiation therapies.
  • Investigational immunotherapy to use a patient’s own immune systems to attack their cancer.

We’re with you every step of the way.

Our care continues after your treatment. We offer a full suite of physical, occupational, speech and other rehabilitation and recovery therapies. We also can work with your local providers on a plan designed to regain any main function lost or impaired during treatment.


If you'd like to connect with others who have or are dealing with brain cancer, our Brain Cancer Support Group is a great place to start.


Our teams in the Midwest, in Arizona, and Florida collaborate, so you get all the benefit of Mayo Clinic expertise at every location.

Nationally recognized for expertise.

Mayo Clinic in Arizona, a National Cancer Institute (NCI) designated Comprehensive Cancer Center, has been ranked #1 in the state of Arizona for Neurology and Neurosurgery, and Cancer care.


Mayo Clinic in Arizona’s Neurology and Neurosurgery specialties are recognized on Newsweek’s World’s Best Specialized Hospitals 2025 list.

Many insurance plans accepted.

Mayo Clinic has agreements with many insurance carriers, third-party administrators, and employers.

Contact us to request an appointment.

Phoenix, AZ

5777 E. Mayo Blvd.

Phoenix, AZ 85054

8 a.m. to 5 p.m. Mountain Time

Jacksonville, FL

4500 San Pablo Road

Jacksonville, FL 32224

8 a.m. to 5 p.m. Eastern Time

Rochester, MN

200 First St. SW,

Rochester, MN 55905

7 a.m. to 6 p.m. Central Time

Why Choose Mayo Clinic for Brain Tumor Care

Mayo Clinic is a fantastic place to have multidisciplinary care for highly complex patients. The Brain Tumor Program here is flourished with people who really care about what they do. Collectively, we perform thousands and thousands of brain tumor procedures every year, and there just isn't really anywhere else in the country or to my knowledge around the world that could equal that degree of experience. Patients will even ask me is like, wow, this is a really rare disease. And I'll say, well, yes, it is rare, but we are a referral center and we see these unusual, uncommon diseases to us. And so as a team, it's not rare, so maybe one in a million out there, but it's certainly not one in a million here. One of the things that we do here is make sure that we can see people almost right away. We have a policy that we'll see anybody with a brain tumor within 48 hours if they want to be seen that quickly. Time is critical, for the management of patients with brain cancers. Our practices are such that, you know, we find it really easy to contact our neurosurgeons or radiation oncologists and get insights into the care of the patient immediately so that we can handle patient care at that moment. One of the things that we've been also thinking about is the time the patients spend here at the clinic and what's the financial toxicities to them and what does it mean to their life. So a lot of our approaches is also exploring shorter courses of radiation and targeted better with our new diagnostic technologies that we have. We also have one of the largest, if not the largest group of MRI magnets at three Tesla, which is kind of the higher standard clinical grade. We also had the first seven Tesla magnet, the strongest magnet approved for clinical use in brain imaging that was first developed and put into use clinically here at Mayo Clinic. And so that just gives us, an added degree of information, that we wouldn't have otherwise. Our nuclear medicine department here is spectacular and have led the way with a number of novel PET scans for metabolic imaging, which we have used at least experimentally, to guide surgery, to guide radiation treatments for brain tumors with excellent outcomes. We are always pushing the boundaries for new treatments. I tell patients we're better at treating brain tumors now than we were a year ago or five years ago, and we're gonna be better a year from now, or five years from now. So that depth of expertise really makes a difference. Mayo Clinic represents hope for many patients. We really do provide comprehensive, world-class care. It really is a great team. There are not many other places in the world that have the same degree of experiences as we have, and that matters for the outcomes for patients.

Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy below.

A single copy of these materials may be reprinted for noncommercial personal use only. “Mayo,” “Mayo Clinic,” “MayoClinic.org,” “Mayo Clinic Healthy Living,” and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

© 1998-2025 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved.