Jacksonville, FL

8 a.m. to 5 p.m. Eastern Time

World-Class Care for Brain Cancer Begins Here

Appointments available within 24 hours.

At Mayo Clinic, we continue to innovate so you can focus on life beyond brain cancer. We bring together a team of experts specialized in your individual tumor type who create an individualized care plan for your needs – one that includes all aspects of treatment, recovery, and quality of life.


  • Reduced hospital stays. Many people who undergo brain tumor surgery at Mayo Clinic leave the hospital in one or two days.
  • Lower complication rates. Technological advances allow our surgeons and radiation oncologists to avoid injury to healthy brain tissue.
  • Shorter recovery time. Minimally invasive procedures often result in smaller incisions and scars.
  • Improved quality of life. We manage side effects and work to preserve and maintain motor and cognitive function, speech, cosmetic outcomes, and psychological well-being.
  • Be seen quickly. 24 hour guaranteed access to an appointment. 

Why choose Mayo Clinic for...

Brain Tumor Care

Neurology & Neurosurgery

Types of Brain Tumors & Treatments

7 Tesla MRI

We operate on tumors that other centers may not.

With our expertise and technology, we often treat people with Stage 3 or 4, or metastatic brain cancer. More than 7,000 adults and children with brain and other central nervous system cancers come to Mayo Clinic each year.

Getting a second or third opinion at Mayo Clinic for an advanced or “inoperable” tumor is about finding options and the best possible outcome for you.  

Surgical innovations for safer procedures.

We use advanced technologies to operate closer to vital areas of the brain with confidence and make procedures safer.


  • 3-D printing, augmented reality, and holography to plan the least invasive approach to surgery.
  • Intraoperative MRI (iMRI) to map the brain and maintain functional areas.
  • Awake brain surgery also known as an awake craniotomy allows the Mayo Clinic surgical team to ask questions of the patient and monitor activity in the brain during the responses. This back-and-forth helps ensure the surgery to remove a tumor isn't affecting the patient's communication and cognition skills.
  • Fluorescence-guided surgery to visualize the tumor’s location more precisely.
  • Minimally invasive, scarless brain surgery to enable faster recovery with fewer side effects. Approaches include key-hole surgery, radiosurgery, and laser thermal ablation.

The power of advanced diagnostics.

We analyze the tumor and your healthy brain tissue using advanced approaches, so we can make treatment decisions that are more precise and personalized for you.

  • Molecular diagnostics to analyze your tumor’s DNA and predict which treatments will work best for your specific tumor type.
  • Functional and metabolic activity analysis to learn about tumor metabolism and functioning of the surrounding area.
  • Tumor firmness and adhesion analysis to determine the tumor’s firmness and adhesion to healthy brain tissue, so your surgical team can plan with precision. This state-of-the art technology was invented at Mayo Clinic.
  • 7 – Tesla MRI - This imaging system uses a stronger magnetic field to produce more detailed images of the body's interior. Detailed brain scans help Mayo Clinic care teams diagnose and treat patients with brain tumors. This advanced imaging technology is key to ensuring patients receive an accurate diagnosis to guide treatment. 

Seeing the unseeable with new imaging technology 

This image displays the radiology scanned imaging from a 3 Tesla MRI. The 3 Tesla MRI, while using a less powerful magnetic field compared to the 7 Tesla MRI, still provides clear and detailed images of the body's interior. It is commonly used in clinical settings to diagnose and monitor various medical conditions, offering valuable insights for patient care and treatment planning. However, the clarity of the images produced by the 3 Tesla MRI is not as high as that of the 7 Tesla MRI, which can impact the level of detail visible in the scans.

This image showcases the radiology scanned imaging from a 7 Tesla MRI. The 7 Tesla MRI uses a stronger magnetic field to produce highly detailed images of the body's interior. The detailed brain scans generated by this advanced imaging system assist Mayo Clinic care teams in diagnosing and treating patients with brain tumors. This cutting-edge technology is crucial for ensuring patients receive accurate diagnoses, which guide effective treatment plans.

Therapies designed to minimize side effects.

Our radiation therapies are designed to target tumor cells and minimize effects on healthy brain tissue.

  • Stereotactic radiosurgery includes Gamma Knife®, which delivers a high dose of radiation to a very small area of the brain.

Innovative treatments and clinical trials.

Our physicians conduct research to bring advancement to patients faster with treatments and clinical trials. You can find the latest brain tumor clinical trials at  Mayo Clinic.


Research includes:

  • The most effective combination of medications and radiation therapies.
  • Investigational immunotherapy to use a patient’s own immune systems to attack their cancer.

We’re with you every step of the way.

Our care continues after your treatment. We offer a full suite of physical, occupational, speech and other rehabilitation and recovery therapies. We also can work with your local providers on a plan designed to regain any main function lost or impaired during treatment.


If you'd like to connect with others who have or are dealing with brain cancer, our Brain Cancer Support Group is a great place to start.


Our teams in the Midwest, in Arizona, and Florida collaborate, so you get all the benefit of Mayo Clinic expertise at every location. 

Highly ranked expertise. 

Mayo Clinic in Jacksonville, Florida, rank among the Best Hospitals for Neurology and Neurosurgery in the U.S. News & World Report Best Hospitals rankings.


In recognition of our scientific leadership in cancer care and research, Mayo Clinic was one of the first National Cancer Institute (NCI)-designated comprehensive cancer centers and is the only such center with three unique locations today. Mayo Clinic Comprehensive Cancer Center meets the strict standards for scientific excellence and a multispecialty approach focused on cancer prevention, diagnosis, and treatment.


One of the National Cancer Institute’s first designated Comprehensive Cancer Centers. Proudly recognized for our scientific leadership and resources.

Meet our team.

Alfredo Quinones-Hinojosa, M.D.

Kaisorn Chaichana, M.D.

Rich W. Byrne, M.D.

Neurosurgery

Neurosurgery

Neurosurgery

Wendy J. Sherman, M.D.

Kurt A. Jaeckle, M.D.

Steven S. Rosenfield, M.D.

Neuro-Oncology

Neuro-Oncology

Neuro-Oncology

Jennifer L. Peterson, M.D.

Daniel Trifiletti, M.D.

David S. Sabsevitz, Ph.D., APBB

Radiation Oncology

Radiation Oncology

Neuropsychology

Contact us to request an appointment.

Phoenix, AZ

5777 E. Mayo Blvd.

Phoenix, AZ 85054

8 a.m. to 5 p.m. Mountain Time

Jacksonville, FL

4500 San Pablo Road

Jacksonville, FL 32224

8 a.m. to 5 p.m. Eastern Time

Rochester, MN

200 First St. SW,

Rochester, MN 55905

7 a.m. to 6 p.m. Central Time

Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy below.

A single copy of these materials may be reprinted for noncommercial personal use only. “Mayo,” “Mayo Clinic,” “MayoClinic.org,” “Mayo Clinic Healthy Living,” and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

© 1998-2025 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved.