Phoenix, AZ: 520-649-8104

8 a.m. to 5 p.m.

Mountain time, Monday through Friday

At Mayo Clinic in Arizona, you’ll have a whole team of epilepsy experts who take the time to listen, provide the right diagnosis, and personalize your treatment. We have successfully treated even the most complex cases, offering options for people with uncontrolled seizures and multiple conditions.  

Mayo Clinic is a Level 4 Comprehensive Epilepsy Center – the highest-level designation by the National Association of Epilepsy Centers. Over 8,000 adults and children who have epilepsy come to us each year. Whether you are newly diagnosed, or have lived for years with a seizure disorder, the expert teams at Mayo Clinic in Arizona will use advanced imaging and diagnostic studies to detect abnormalities causing epilepsy and to help guide your treatment. Getting a second opinion with Mayo Clinic’s experts might uncover new treatments for you. 

Mayo Clinic remains a leader in healthcare innovation, applying advanced technologies like the 7-Tesla MRI to help improve patient care. We analyze your brain tissue using advanced approaches, so we can make treatment decisions that are more precise and personalized for you.

• 7 – Tesla MRI - This imaging system uses a stronger magnetic field to produce more detailed images of the body's interior. Detailed brain scans help Mayo Clinic care teams diagnose and treat patients with epilepsy. This advanced imaging technology is key to ensuring patients receive an accurate diagnosis to guide treatment.
• Morphometric Analysis programing
• Simultaneous position emission tomography MRI

Because our physicians are also researchers and educators, Mayo Clinic is on the forefront of new diagnostic and treatment approaches and clinical trials. These include: 

• New approaches developed by Mayo Clinic researchers to diagnose and treat autoimmune epilepsy.
• Genetic testing for complex conditions.
• Options for people with drug-resistant epilepsy including clinical trials, neurostimulation devices and, in some cases, surgery. 

Surgical approaches:

• Extraoperative brain mapping, including grid insertion and stereotactic electroencephalogram, to locate the seizure source and determine if removing brain tissue will cure seizures while maintaining other function. 
• Stereotactic minimally invasive laser surgery to ablate (burn away) the area of the brain causing seizures. 
• Neuromodulation, including deep-brain stimulation, responsive neurostimulation, and vagus nerve stimulation, to stimulate a specific area and stop a major seizure when it begins, using devices and electrodes. It’s an option when the seizure area cannot be removed. 
• Temporal lobectomy, a treatment that involves a brain resection and is used in select cases to reduce frequency and severity of seizures or stop them completely. 

Based on the cause of your seizure disorder, we will create an individualized care plan for you that may include: 

• Medications carefully selected to fit your needs.
• Surgery to remove or disrupt the area where seizures originate.
• Stimulation therapy to disrupt seizure patterns in the brain.
• Dietary considerations, such as the ketogenic diet, to impact seizure frequency. 

At Mayo Clinic, epilepsy treatment is more than neurology. We bring together multiple experts across medical specialties to understand the cause of your epilepsy and determine the best treatment for your seizures and address all your health care needs.  

Mayo Clinic in Arizona’s Neurology and Neurosurgery specialties are recognized on Newsweek’s World’s Best Specialized Hospitals 2025 list.

Mayo Clinic is top ranked in more specialties than any other hospital, according to U.S. News & World Report.

While U.S. News only reports national specialty rankings and doesn't rank specialties at the regional or state level, Mayo Clinic evaluates whether a hospital outperforms others in its region or state based on national rankings.

5777 E. Mayo Blvd.

Phoenix, AZ 85054

520-649-8104

8 a.m. to 5 p.m.

Mountain time, Monday through Friday

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