Rochester, MN: 507-538-3270

Jacksonville, FL: 904-953-0853

Phoenix, AZ: 480-301-8484

An Entire Team Focused on You – Not Just Your Epilepsy

At Mayo Clinic, you’ll have a whole team of epilepsy experts who take the time to listen, provide the right diagnosis, and personalize your treatment. We have successfully treated even the most complex cases, offering options for people with uncontrolled seizures and multiple conditions.  

Successful treatment starts with accurate diagnosis.

Mayo Clinic is a Level 4 Comprehensive Epilepsy Center – the highest-level designation by the National Association of Epilepsy Centers. Over 8,000 adults and children who have epilepsy come to us each year. Whether you are newly diagnosed, or have lived for years with a seizure disorder, the expert teams at our locations in Arizona, Florida and Minnesota will use advanced imaging and diagnostic studies to detect abnormalities causing epilepsy and to help guide your treatment. Getting a second opinion with Mayo Clinic’s experts might uncover new treatments for you. 

  • We use Positron emission tomography MRI
  • Single photon emission computerized tomography
  • Subtraction ictal single-photon emission computed tomography (SPECT) coregistered with MRI
  • Statistical parametric mapping-based methods
  • High-frequency oscillation density mapping
  • Stereo electroencephalogram
  • Functional MRI
  • Morphometric Analysis Program imaging
  • Simultaneous positron emission tomography MRI
  • More tests including the 7-Tesla MRI available at Mayo Clinic's Minnesota campus — the first clinically available in the U.S.

Innovative treatment options and advanced surgical approaches.

Because our physicians are also researchers and educators, Mayo Clinic is on the forefront of new diagnostic and treatment approaches and clinical trials. These include: 

  • New approaches developed by Mayo Clinic researchers to diagnose and treat autoimmune epilepsy.
  • Genetic testing for complex conditions.
  • Options for people with drug-resistant epilepsy including clinical trials, neurostimulation devices and, in some cases, surgery. 

Surgical approaches:

  • Extraoperative brain mapping, including grid insertion and stereotactic electroencephalogram, to locate the seizure source and determine if removing brain tissue will cure seizures while maintaining other function. 
  • Stereotactic minimally invasive laser surgery to ablate (burn away) the area of the brain causing seizures. 
  • Neuromodulation, including deep-brain stimulation, responsive neurostimulation, and vagus nerve stimulation, to stimulate a specific area and stop a major seizure when it begins, using devices and electrodes. It’s an option when the seizure area cannot be removed. 
  • Temporal lobectomy, a treatment that involves a brain resection and is used in select cases to reduce frequency and severity of seizures or stop them completely. 

Based on the cause of your seizure disorder, we will create an individualized care plan for you that may include: 

  • Medications carefully selected to fit your needs.
  • Surgery to remove or disrupt the area where seizures originate.
  • Stimulation therapy to disrupt seizure patterns in the brain.
  • Dietary considerations, such as the ketogenic diet, to impact seizure frequency. 

We’re with you every step of the way.

At Mayo Clinic, epilepsy treatment is more than neurology. We bring together multiple experts across medical specialties to understand the cause of your epilepsy and determine the best treatment for your seizures and address all your health care needs.  

Highly ranked for neurology and neurosurgery. 

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida have been ranked among the best Neurology & Neurosurgery Hospitals in the nation by U.S. News & World Report. 

When it's time to find answers, you know where to go.

Contact us to request an appointment.

Arizona

Rochester

Florida

5777 E. Mayo Blvd.

Phoenix, AZ 85054

480-301-8484

4500 San Pablo Road

Jacksonville, FL 32224

904-953-0853

200 First St. SW,

Rochester, MN 55905

507-538-3270

What is epilepsy? A Mayo Clinic expert explains.

Hi, I'm Dr. Lily Wong-Kisiel, a pediatric neurologist at Mayo Clinic. And this video will cover the basics of epilepsy. What is it? Who gets it? The symptoms, diagnosis, and treatment. Whether you're looking for answers for yourself or someone you love, we're here to give you the best information available. First of all, epilepsy is common. Around 3 million people in the US have epilepsy, making it the fourth most common neurological disease after migraine, stroke and Alzheimer's. Epilepsy happens as a result of abnormal electrical brain activity, also known as a seizure, like an electrical storm inside your head. Because your brain controls so much, a lot of different things can go wrong. You may have periods of unusual behaviors, feelings, and sometimes loss of awareness. There are many types of seizures, including two main categories. Focal, meaning, they start in a particular part of your brain. Or generalized, meaning, the seizures initially involves all areas of the brain.

There are some myths about epilepsy we can dismiss. If you are with someone experiencing a seizure, don't put anything in their mouth. They can't actually swallow their tongue. Don't restrain them, and don't worry, epilepsy isn't contagious, so you can't catch it. Although children or older adults are more susceptible, anyone can develop epilepsy. When epilepsy is diagnosed in older adults, it's sometimes from another neurological issue, like a stroke or a brain tumor. Other causes can be related to genetic abnormalities, prior brain infection, prenatal injuries, or developmental disorders. But in about half of people with epilepsy, there is no apparent cause. Because they happen in the brain, seizures can affect any process your brain handles. Therefore, symptoms can vary. Many individuals of the epilepsy tend to have the same type of seizure each time. However, some will have more than one type.

So how do you recognize a seizure? Keep an eye out for temporary confusion, a staring spell, uncontrollable jerking, loss of consciousness, fear, anxiety, or deja vu. Let's talk about the two types of seizures again. Focal and generalized. Focal seizures happen one of two ways, without loss of awareness or with impaired awareness. And those where you remain conscious, you may experience altered emotions or change in sensation, like smell, sound, or taste. You may also have dizziness, tingling, or see flashing lights. You could also experience involuntary jerking of body parts, like your arm or your leg. When you lose or have altered awareness, you can pass out or stare into space and not really respond normally. Hand rubbing, chewing, swallowing, or walking in circles can happen in this kind of seizure. Because these symptoms overlap with migraine or other neurological disorders, heart problems, or psychiatric conditions, tests are needed for a diagnosis. Generalize onset seizures, the ones that happen across all areas of the brain, show up in a variety of ways. Absence seizures are marked by staring absently into space. Blinking and lip smacking can also happen. Tonic seizures involve a stiffening of the back, arm, and legs. The opposite of tonic seizures are atonic seizures, which result in a loss of muscle control. Instead of going stiff, everything goes slack. Clonic seizures usually affect the neck, face, and arms with repeated jerking movements similar to clonic seizure. Myoclonic seizures involve sudden, brief jerks or twitches of your arms. Lastly, there are tonic clonic seizures, like the name suggests, these involve parts of both tonic and clonic signs. Body stiffening and shaking, loss of bladder control, or biting your tongue can also happen. Knowing the kind of seizure you have is key to treatment.

Even after having a single seizure, sometimes the diagnosis of epilepsy can't be made. Regardless, if you do have something that seems like a first time seizure, see a physician. Your doctor may assess your motor abilities, mental function, and other areas to diagnose your condition and determine if you have epilepsy. They may also order additional diagnostic tests. They could include neurological exam, blood tests, EEG, CT scan, brain imaging, and sometimes neuropsychological tests. Because your brain is such a complicated piece of machinery, neurologists, epileptologists, neurosurgeons, neuroradiologists, mental health specialist, and other professionals all work together to provide exactly the care you need. The best care starts with an accurate diagnosis. The medications we have for epilepsy are incredibly effective. More than half of the cases are seizure free after their first medication. But when medication does not work at stopping seizures completely. There are other emerging ways of treating epilepsy, including surgery and brain stimulation. At a comprehensive level four epilepsy center can help find you the best way to manage your care. For patients undergoing treatment, it's important to keep a detailed seizure journal. Each time you have a seizure, write down the time, the type, and how long it lasted. Making note of anything out of the ordinary like mis medication, sleep deprivation, increased stress, menstruation, or anything else that could trigger it. But we don't always know why people suffer from epilepsy. Ongoing research continues to build our knowledge and improve treatment options. And better treatment means happier patients. If you'd like to learn even more about epilepsy, watch our other related videos or visit MayoClinic.org We wish you well.

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