Phoenix, AZ:  520-534-1896

Rochester, MN: 507-718-5819

Jacksonville, FL: 904-984-8196

Expert Care for Complex and Advanced Kidney Cancer: Hope at Mayo Clinic

We are making the untreatable treatable. At Mayo Clinic Comprehensive Cancer Center in Arizona, we offer hope for people with complex kidney tumors and metastatic kidney cancer. Through accurate diagnoses and deep expertise, Mayo Clinic provides the best possible outcomes and an unmatched care experience. You’ll have access to leading-edge treatments, including immune checkpoint inhibitors, targeted therapy and clinical trials. We aim to cure your cancer while sparing kidney tissue so you may live a longer, higher-quality life.   

Unmatched surgical expertise.

Our surgeons regularly perform highly complex surgeries for kidney cancer, so you can feel confident you’re in expert hands.

  • Kidney preservation. Our surgeons specialize in surgery that aims to cure your cancer while sparing your kidneys, which may help you avoid dialysis and is associated with a longer, improved quality of life.
  • Safer complex surgeries. Our team has vast experience in intricate surgeries and removing tumors intertwined with blood vessels. More surgical experience means better outcomes and survival rates.
  • Surgery for advanced disease. From inoperable to operable. Because of Mayo Clinic’s extensive experience and expertise, we can often treat people for kidney tumors that were considered inoperable elsewhere. At Mayo Clinic in Arizona, multiple specialists assist with complex surgeries involving the largest blood vessels in the body, the aorta and vena cava.
  • Minimally invasive intervention. Our team has a long history of pioneering and refining minimally invasive procedures that can offer shorter recovery times. These operations are usually performed using cutting-edge robotics or through laparoscopic (keyhole) incisions.
  • Excellent pain management. We use less invasive techniques to minimize pain. We also adhere to Enhanced Recovery After Surgery (ERAS) to ensure adequate pain control while optimizing a rapid recovery.
  • Multidisciplinary care. Our surgical team is supported by multiple other teams that can significantly contribute to the success of kidney surgery. This includes our nursing and administrative staff, who help with surgery preparation and post-operative care. We also have a strong history of collaboration with medical oncology to combine surgical and medical management.
  • Ablative treatment. Some kidney cancers do not require surgery. At Mayo Clinic in Arizona, our experienced radiologists can treat some tumors with ablation under image guidance. These procedures are less invasive and involve inserting a small probe through the skin into the tumor to freeze or ablate the tumor. 

The power of seamless collaboration.

Your team consists of global leaders in renal cancer and includes expert urologic surgeons, medical oncologists, pathologists, radiation oncologists, radiologists, anesthesiologists and others as appropriate. They collaborate to provide treatment plans for advanced disease, including stage 4 kidney cancer with metastasis, so you get the best possible prognosis and outcome. 

Our top priority, your best possible outcome.

Your expert kidney cancer team at Mayo Clinic prioritizes your chance of achieving a cure and the highest quality of life with the least symptoms and side effects. We extend our expertise in care coordination, working with your local care team so you have a seamless transition back home.


Mayo Clinic is the #1 cancer hospital in Arizona, according to U.S. News & World Report. We are a National Cancer Institute-designated comprehensive cancer center with three locations. This esteemed designation means we are driving the future of groundbreaking research, clinical trial access, and innovative therapies. 

When it's time to find answers, you know where to go.

Contact us to request an appointment.

Arizona

Florida

Rochester

5777 E. Mayo Blvd.

Phoenix, AZ 85054

520-534-1896

4500 San Pablo Road

Jacksonville, FL 32224

904-984-8196

200 First St. SW,

Rochester, MN 55905

507-718-5819

Complex and Metastatic Kidney Cancer – Multispecialty Care Clinic Provides Personalized Treatment.

One of the most exciting things that we can tell you about treating kidney cancer at Mayo Clinic is we have learned exactly who actually needs treatment, and many people do not. For people that need treatment, we figured out how to treat people with a higher likelihood of cure than ever and less impact on them in terms of recovery, functional loss, or any negative impact on quality of life. By coming to Mayo Clinic, you're really availing yourself to expertise specific to kidney cancer, complex kidney cancer, and metastatic kidney cancer. What our goal is, is to help with higher level complex decision making. And really guide any specific treatments that need to be done at Mayo Clinic.

Whether that be a clinical trial, complex surgical interventions, or other sorts of localized focused therapies. At Mayo Clinic, we developed a multidisciplinary care clinic for patients with kidney cancer where I sit in clinic with one of my colleagues. And we do clinic together so that we can give each patient that comes to see us, not only a surgical opinion but a medical oncology opinion, and offer the best choices for our patients with one stop. You're always going to be more comfortable with the management of your kidney cancer if you've had a second opinion and there's agreement. At any given time, we have complete ability to talk to pathologists, to talk to interventional radiologists, to talk to diagnostic radiologist, to talk to radiation oncology. Those are really the key people who we rely on in this space. But the beauty of Mayo Clinic also is that it's a multi specialty integrated practice.

If there is another surgical specialist who needs to get involved, we really have access to those people very quickly. Any patient anywhere around the world could get a video visit with urology here at Mayo Clinic. And we're very collaborative with the home doctors to help really bring to bear the best of Mayo Clinic and the expertise here. But also with the safety and convenience of being treated by an oncology expert closer to home. Patients that come to Mayo Clinic benefit not only from expertise in routine standard of care, but from the fact that we're doing significant research that has shaped how we treat kidney cancer today. And we're doing the research to assure that we're doing even better with treating kidney cancer tomorrow and beyond.

Mayo Clinic Comprehensive Cancer Center is designated by the National Cancer Institute as a comprehensive cancer center.

Mayo Clinic Comprehensive Cancer Center is nationally accredited by the American College of Surgeons' Commission on Cancer (CoC).

Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy below.

A single copy of these materials may be reprinted for noncommercial personal use only. “Mayo,” “Mayo Clinic,” “MayoClinic.org,” “Mayo Clinic Healthy Living,” and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

© 1998-2025 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved.