Liver Cancer Care - Mayo Clinic

At Mayo Clinic, you'll receive expert care delivered with compassion and designed with you in mind. From the most advanced diagnostic and treatment tools to complete survivorship programs, your Mayo Clinic care team aims to help you thrive through and beyond treatment.

We prioritize your needs in all areas of treatment, recovery and quality of life. Your multidisciplinary team has deep expertise in treating primary liver cancer. This includes both hepatocellular carcinomas – cancers that develop from liver cells which often occur in people with existing liver disease – and cholangiocarcinoma, which develops in the bile ducts.

We bring together an entire team of specialists to treat your liver cancer together. This includes:

Liver specialists (hepatologists)
Liver surgeons (hepatobiliary surgeons)
Transplant surgeons
Medical and radiation oncologists
Interventional and diagnostic radiologists

Our hepatobiliary neoplasia clinic has dedicated teams of specialists who focus on liver cancer, so you get the right answers and best treatment options. We care about what matters to you and will create a personalized plan to help you achieve your treatment and quality-of-life goals, using innovative treatments and advanced technologies.

Mayo Clinic is a leading center in the U.S. for liver cancer treatment. We have experts and outcome-focused care designed to help you recover and get back to the things that matter to you.

You’ll also have access to:

Minimally invasive liver surgery
Deceased and living donor liver transplantation
Less invasive nonsurgical techniques including ablation, embolization, and radioembolization
Stereotactic body radiotherapy (SBRT) and proton beam therapy to precisely target cancer with fewer side effects
Targeted therapy and immunotherapy
Clinical trials
Personalized treatments based on your genes, for greater effectiveness and potentially fewer side effects

Research and clinical trials in liver cancer are supported by a National Cancer Institute (NCI)-funded SPORE grant.

Innovative Treatment in Liver Cancer

Liver cancer is particularly complex type of disease to treat. When a patient is diagnosed with liver cancer, they are looking for alternative options that are possible to them and here at the Mayo Clinic, we are always trying to stretch that boundary. It allows us to put the best interests of the patient front and center so that we can take care of patients. We can develop new tools to diagnose and treat patients and really provide hope for these patients with liver cancer. There have been a large number of advances in the care of patients with both primary and secondary liver cancers. Mayo Clinic has been a pioneer in the application of pencil beam technology, and this affords the ability in the right patients to be able to use radiation therapy with minimal side effects. Mayo Clinic has a large program investigating drugs that are still in clinical trials that can be accessed by patients for the care of their liver cancer. If a patient is not a candidate for surgery, we will work in interventional oncology to try to remodel the liver to make that patient a candidate for surgery. If the patient cannot have a perspective, then we'll do our best approaches to identify a pattern of disease which we know that traditionally may not have benefited from surgery, but that can benefit from local therapies and interventional oncology. Our Tumor Board is really the central focus of our patient-centered activity. It's where we make the most decisions. The greatest thing is getting that room together of really national and international experts in all aspects of liver cancer care together to really discuss what the best treatment options are for each individual patient and then how to enact that plan with their local providers. And ultimately, our biggest goal is to try to bring a patient to a curative intent when possible, and to optimize quality of life across all treatment regimens that we provide.

Liver Cancer Treatment Centered Around You

We’re with you every step of the way.

Innovation for better outcomes.

When it's time to find answers, you know where to go.

Contact us to request an appointment.

Innovative Treatment in Liver Cancer

Mayo Clinic Comprehensive Cancer Center is designated by the National Cancer Institute as a comprehensive cancer center.

Mayo Clinic Comprehensive Cancer Center is nationally accredited by the American College of Surgeons' Commission on Cancer (CoC).