Rochester, MN

7 a.m. to 6 p.m. CST

MOGAD Clinic provides leading expertise at Mayo Clinic

Mayo Clinic’s MOGAD Clinic is uniquely equipped to provide accurate diagnosis and treatment for children and adults with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). At Mayo Clinic you’ll be seen by the world's foremost experts in MOGAD.


We conduct research toward improving diagnosis and treatment and apply proven breakthrough discoveries in our MOGAD Clinic. Mayo Clinic evaluates more than 100 children and adults with MOGAD each year. 

The peace of mind of an expert second opinion.

MOGAD is a newly defined autoimmune disorder that can look like multiple sclerosis (MS) or other diseases but requires different treatment. Getting a second opinion at Mayo Clinic’s MOGAD Clinic can provide peace of mind or point you to more treatment options. Our experts in MOGAD can provide a thorough evaluation and answer any questions you may have. 

Advanced diagnosis and treatment.

Our onsite neuroimmunology laboratory performs myelin oligodendrocyte glycoprotein (MOG) antibody testing and interpretation. Since MOG antibody can be found at low levels with other disorders and create a false positive result, our MOGAD experts can determine if you truly have MOGAD. Additional tests may include MRI scans of the head, eyes and spine, a spinal tap, and an eye exam.


With MOGAD, the body's immune system attacks myelin (the outer covering of nerves), causing inflammation in the brain, optic nerve, or spinal cord. Our neurologists and radiologists are experts in approaches to treat and prevent attacks. Clinical trials are also underway at Mayo Clinic to identify effective treatments.


The MOGAD Clinic also provides comprehensive approaches to manage symptoms like vision loss, muscle weakness, stiffness or paralysis, bowel or bladder problems, confusion, seizures, and headaches. Treatments include oral corticosteroids, urology procedures, injections to control spasticity, plasma exchange, high-dose intravenous steroids, IV immunoglobulin (also called IVIg), occupational therapy, and physical therapy. 

Our team-based, personalized approach.

We bring together all the specialists you may need to provide a personalized plan of care in a timely way. Your team may include specialists in neurology, neuroimmunology, neuro-ophthalmology, physical medicine and rehabilitation, urology, neuropsychology, neuroradiology, pain medicine, laboratory medicine and pathology. If you like, we can send a full report to your primary care professional or other referring healthcare professional.


Because children are more likely to have MOGAD, access to a pediatric MOGAD expert is important. The MOGAD Clinic in Minnesota coordinates with a team of pediatric doctors who specialize in conditions that affect children. 

Seeing the unseeable with new imaging technology 

This image displays the radiology scanned imaging from a 3 Tesla MRI. The 3 Tesla MRI, while using a less powerful magnetic field compared to the 7 Tesla MRI, still provides clear and detailed images of the body's interior. It is commonly used in clinical settings to diagnose and monitor various medical conditions, offering valuable insights for patient care and treatment planning. However, the clarity of the images produced by the 3 Tesla MRI is not as high as that of the 7 Tesla MRI, which can impact the level of detail visible in the scans.

This image showcases the radiology scanned imaging from a 7 Tesla MRI. The 7 Tesla MRI uses a stronger magnetic field to produce highly detailed images of the body's interior. The detailed brain scans generated by this advanced imaging system assist Mayo Clinic care teams in diagnosing and treating patients with brain tumors. This cutting-edge technology is crucial for ensuring patients receive accurate diagnoses, which guide effective treatment plans.

Why choose Mayo Clinic for:

MOGAD Care

Neurology & Neurosurgery

Top ranked.

Mayo Clinic in Rochester, Minnesota is ranked #1 for Neurology and Neurosurgery in the Midwest by U.S. News and World Report.


Mayo Clinic in Rochester, Minnesota is ranked #1 for Neurology care by Newsweek’s World’s Best Specialized Hospitals 2025 list.

When it's time to find answers, you know where to go.

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