Our onsite neuroimmunology laboratory performs myelin oligodendrocyte glycoprotein (MOG) antibody testing and interpretation. Since MOG antibody can be found at low levels with other disorders and create a false positive result, our MOGAD experts can determine if you truly have MOGAD. Additional tests may include MRI scans of the head, eyes and spine, a spinal tap, and an eye exam.
With MOGAD, the body's immune system attacks myelin (the outer covering of nerves), causing inflammation in the brain, optic nerve, or spinal cord. Our neurologists and radiologists are experts in approaches to treat and prevent attacks. Clinical trials are also underway at Mayo Clinic to identify effective treatments.
The MOGAD Clinic also provides comprehensive approaches to manage symptoms like vision loss, muscle weakness, stiffness or paralysis, bowel or bladder problems, confusion, seizures, and headaches. Treatments include oral corticosteroids, urology procedures, injections to control spasticity, plasma exchange, high-dose intravenous steroids, IV immunoglobulin (also called IVIg), occupational therapy, and physical therapy.