MOGAD Clinic - Mayo Clinic

Our onsite neuroimmunology laboratory performs myelin oligodendrocyte glycoprotein (MOG) antibody testing and interpretation. Since MOG antibody can be found at low levels with other disorders and create a false positive result, our MOGAD experts can determine if you truly have MOGAD. Additional tests may include MRI scans of the head, eyes and spine, a spinal tap, and an eye exam.

With MOGAD, the body's immune system attacks myelin (the outer covering of nerves), causing inflammation in the brain, optic nerve, or spinal cord. Our neurologists and radiologists are experts in approaches to treat and prevent attacks. Clinical trials are also underway at Mayo Clinic to identify effective treatments.

The MOGAD Clinic also provides comprehensive approaches to manage symptoms like vision loss, muscle weakness, stiffness or paralysis, bowel or bladder problems, confusion, seizures, and headaches. Treatments include oral corticosteroids, urology procedures, injections to control spasticity, plasma exchange, high-dose intravenous steroids, IV immunoglobulin (also called IVIg), occupational therapy, and physical therapy.

Symptoms can include vision loss, muscle weakness, stiffness or paralysis, bowel or bladder problems, confusion, seizures, and headaches. Symptoms can be confused with related disorders, such as multiple sclerosis.

Our neurologists, radiologists and neurosurgeons are experts in medical and therapeutic care for people with MOGAD. We offer treatments including:

Oral corticosteroids
Urology procedures
Injections to control spasticity
Plasma exchange
High-dose intravenous steroids
IV immuneglobulin ( IVIg)
Occupational therapy
Physical therapy

Because MOGAD can affect many parts of the body, your care team might include specialists in neurology, neuroimmunology, neuro-ophthalmology, physical medicine and rehabilitation, urology, neuropsychology, neuroradiology, pain medicine, or laboratory medicine and pathology. Your team works together to make sure you get exactly the care you need. The MOGAD Clinic at Mayo Clinic in Minnesota coordinates with a team of doctors who specialize in conditions that affect children. 

We provide MOG antibody testing and expert interpretation of results at our onsite neuroimmunology lab.

We bring together all the specialists you may need to provide a personalized plan of care in a timely way. Your team may include specialists in neurology, neuroimmunology, neuro-ophthalmology, physical medicine and rehabilitation, urology, neuropsychology, neuroradiology, pain medicine, laboratory medicine and pathology. If you like, we can send a full report to your primary care professional or other referring healthcare professional.

Because children are more likely to have MOGAD, access to a pediatric MOGAD expert is important. The MOGAD Clinic in Minnesota coordinates with a team of pediatric doctors who specialize in conditions that affect children.

This image displays the radiology scanned imaging from a 3 Tesla MRI. The 3 Tesla MRI, while using a less powerful magnetic field compared to the 7 Tesla MRI, still provides clear and detailed images of the body's interior. It is commonly used in clinical settings to diagnose and monitor various medical conditions, offering valuable insights for patient care and treatment planning. However, the clarity of the images produced by the 3 Tesla MRI is not as high as that of the 7 Tesla MRI, which can impact the level of detail visible in the scans.

MOGAD Clinic provides leading expertise at Mayo Clinic

The peace of mind of an expert second opinion.

Advanced diagnosis and treatment.

Specialists in Diagnosis and Care for MOGAD

Our team-based, personalized approach.

Seeing the unseeable with new imaging technology

Why choose Mayo Clinic for:

MOGAD Care

Neurology & Neurosurgery

Nationally recognized expertise.

When it's time to find answers, you know where to go.

Contact us to request an appointment.

Mayo Clinic Children’s Center in Rochester, Minnesota is a Level 1 Children’s Surgery Center, the highest verification awarded by the American College of Surgeons (ACS).