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The Littlest People Need Big Cancer Expertise

Mayo Clinic Children’s Center offers advanced treatments, innovative technology and pediatric cancer expertise you won’t find everywhere else.


Treatment of cancer in children can be very different than in adults. At Mayo Clinic Children’s Center, pediatric cancer experts work together to deliver effective, individualized treatment plans in a child and family-friendly environment.

Latest treatment and technology.

  • Mayo Clinic is the only center in the region providing proton beam therapy, which spares healthy tissues and prevents damage to developing organs meaning fewer health issues later in life, including growth problems, hearing and vision loss, heart disease and additional cancers.
  • CAR-T cell and other immunotherapies.
  • Autologous and allogeneic stem cell transplants.
  • Advanced imaging such as 7-tesla MRI to facilitate surgical and proton beam radiation procedure planning.
  • Minimally invasive and robot-assisted surgery which can mean smaller incisions, less pain and quicker recovery.

Clinical trials advance care for children.

Mayo Clinic has a large library of clinical trials, and 90% of eligible patients receive care as part of a clinical trial. Not only does Mayo Clinic develop our own research and trials, but we are also a member of the Children’s Oncology Group. This large collaboration of U.S. hospitals gives children access to clinical trials that offer the latest treatment options for childhood.

Coordinated, comprehensive care teams.

Your care team will include highly trained specialists in hematology and oncology who coordinate comprehensive treatment strategies across pediatric subspecialties, such as:


  • Pediatric multi-disciplinary neuro-oncology and solid tumor programs
  • Pediatric Brain Tumor Clinic
  • Adolescent and Young Adult Cancer Program
  • Fertility Preservation Program
  • Support Services, such as palliative care, specialized nursing, social work, patient education, financial counseling, and chaplaincy program
  • Special Coagulation Laboratory, which is part of Mayo Clinic’s global reference lab and one of the largest clinical labs in the world
  • Comprehensive Hemophilia Treatment Center
  • Non-malignant Blood Disorders


Experts at Mayo Clinic have world class expertise treating all cancers, from the most common to the most rare and complex. In many cases, physician teams at Mayo Clinic are sub-specialized in specific disease areas. We can help children with all cancer diagnoses including:


  • Brain tumors
  • Spinal cord tumors
  • Leukemia
  • Lymphoma
  • Rhabdomyosarcoma
  • Neuroblastoma
  • Nephroblastoma
  • Retinoblastoma
  • Breast cancer
  • Wilms tumor
  • Bone cancers
  • Hemostasis and thrombosis disorders

Top-ranked center.

Mayo Clinic Children's Center is ranked the No. 1 hospital in Minnesota according to U.S. News & World Report's 2024–2025 "Best Children's Hospitals" rankings. These rankings are based on surgical survival, parent and family involvement, clinical research and recommendations by pediatric oncologists and pediatric neurologists and neurosurgeons across the nation.


Mayo Clinic Comprehensive Cancer Center meets strict standards for a National Cancer Institute-designated comprehensive cancer center, recognizing scientific excellence and a multispecialty approach focused on cancer prevention, diagnosis and treatment. 

When it's time to find answers, you know where to go.

Contact us to request an appointment.

Rochester

200 First St. SW, Floor 8

Rochester, MN 55905

507-284-1148

Mayo Clinic Children's Center

Mayo has a 150 year history of excellence and integrity. There's experts in everything at the Mayo Clinic we can apply to the pediatric population. When you're the parent of a child with a rare condition, rears and not rare, rare is your world.

One of the most powerful things that we can do is to listen, reassuring families that they're not alone, we're by their side. For us and the Children's Center, It's the needs of the child and the family that we put first. It's a Children's Hospital, built within the world's best hospital and allows us to provide expertise throughout the continuum of care and make for seamless transitions.

Mayo Clinic Children's Center helps families know there's always hope and you are never alone. The Mayo Clinic Children's Center and you'll see treatments that aren't offered elsewhere. And this is one of the great advantages of an integrated Children's Center. The people that write about medical problems and issues are within our hospital and working with us. Whenever there are new possibilities out there, Mayo Clinic and the staff are very keen to explore new technologies that are on the horizon that could be applied.

We're within a culture that really is based on collaboration and consensus. The sharing of information that is key in helping to care for our children. Providers are in the rooms together talking to each other, sharing information from different specialties. Most of us are parents and most of us have this immediate connection with the parents that do come here. And what is always going through our mind is, if this were our child, this is what we would recommend.

Every single person working together to make sure that you have the best patient experience. There won't be any compromise in terms of what would be best. I've learned more about life through these patients and their family members, how to be resilient, how to appreciate life, the opportunity I have to enter into their world. It's such an honor. All the things that make them, The Mayo Clinic, the best hospital in the world, make the Children's Center what it is..

The needs of the patient come first here at Mayo every time.

Mayo Clinic Comprehensive Cancer Center is designated by the National Cancer Institute as a comprehensive cancer center.

Mayo Clinic Comprehensive Cancer Center is nationally accredited by the American College of Surgeons' Commission on Cancer (CoC).

Mayo Clinic Children’s Center in Rochester, Minnesota is a Level 1 Children’s Surgery Center, the highest verification awarded by the American College of Surgeons (ACS).  

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