Rochester, MN

507-284-8008

Pediatric Complex Care Clinic Extraordinary Care for Extraordinary Kids

When your child needs answers, experience and innovation matter. Experts at Mayo Clinic Children’s Complex Care Clinic specialize in guiding children and families through complex medical journeys with simplified, streamlined and integrated care.


Whether you're still searching for answers or facing a complex diagnosis, our specialized team is here to help. With advanced technology and coordinated care, we work together to find the answers your child needs and guide your family toward a clearer path forward.

Diagnosis to Cure: Aaron's Story

Aaron’s medical journey took a life-changing turn when his undiagnosed symptoms were clarified with a rare diagnosis: X-linked chronic granulomatous disease (CGD). This led to a cure, with the help of a very special participant—a bone marrow transplant from his little brother.

The Right Care Starts Here

Every child’s medical journey is unique—especially when symptoms are complex or unclear. Our comprehensive approach helps uncover the most accurate diagnosis and provides a personalized care plan tailored to your child’s needs. With advanced diagnostics and coordinated expertise, we bring clarity and confidence to care—so your child can start feeling better, faster.

  • 60% of children seen in Mayo Clinic Children’s Complex Care Clinic receive new, updated, or clarified diagnoses after a comprehensive evaluation.
  • 80% of children experience updates to their care management plans following consultation with our team, including over 60% who see adjustments to pharmacotherapy.

Where Answers Begin: Advanced Diagnostics

State-of-the-art diagnostic tools and techniques help us pinpoint underlying conditions. We integrate advanced imaging technologies, genetic testing, and biomarker analyses to gain a comprehensive understanding of each child’s condition. This thorough approach enables us to establish accurate diagnoses and formulate tailored treatment plans.

Big Breakthroughs for Little Patients

At Mayo Clinic Children’s, every child benefits from the full power of Mayo Clinic’s world-renowned research and innovation. From advanced therapies to minimally invasive procedures, we offer treatment options few others can—often developed through the very research happening within our walls. Because at Mayo Clinic, discovery and care go hand-in-hand—so your child has access to the latest proven breakthroughs. 

Integrated, Comprehensive Care for Your Child

Behind every successful outcome is a team that works as one.

Whether your child needs a single specialist or care across multiple pediatric disciplines, our integrated teams collaborate closely to build the most effective care plan—while keeping your child at the center of every decision. With over 300 physicians across 70 pediatric specialties, you're never navigate alone.


Streamlined appointments.

We offer a tightly coordinated schedule that allows children to see multiple specialists within a condensed timeframe. This streamlined approach helps expedite the diagnostic process and the development of a treatment plan, enabling your family to quickly move forward and focus on what matters most — returning to home and your everyday lives.  

Helping Kids Feel Like Kids — Even in the Hospital

Child Life specialists support your child’s emotional well-being through play, preparation, and age-appropriate education. We help kids understand what to expect, reduce fear, and create a more kid-friendly experience. Whether it's a single procedure or a longer stay, we bring comfort, uplifting moments, and guidance to help families navigate their journey with confidence.

Why Families Trust Us—Again and Again

  • Ranked among the nation’s top children’s hospitals
  • No. 1 in the 5-state region of Minnesota, Wisconsin, Iowa, North Dakota and South Dakota for pediatric care (U.S. News & World Report)
  • Designated Level 1 Children’s Surgery Center
  • Home to some of the world’s top pediatric specialists

Families come to us from across the country—and the world—for care they can’t find anywhere else. 

Contact us to request an appointment.

Mayo Clinic in Minnesota

200 First St. SW, 

Rochester, MN 55905

507-284-8008

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