Rochester, MN

507-738-9450

When your child needs answers, experience and innovation matter. Experts at Mayo Clinic Children’s Complex Care Clinic specialize in guiding children and families through complex medical journeys with simplified, streamlined and integrated care.

Whether you're still searching for answers or facing a complex diagnosis, our specialized team is here to help. With advanced technology and coordinated care, we work together to find the answers your child needs and guide your family toward a clearer path forward.

Aaron’s medical journey took a life-changing turn when his undiagnosed symptoms were clarified with a rare diagnosis: X-linked chronic granulomatous disease (CGD). This led to a cure, with the help of a very special participant—a bone marrow transplant from his little brother.

Every child’s medical journey is unique—especially when symptoms are complex or unclear. Our comprehensive approach helps uncover the most accurate diagnosis and provides a personalized care plan tailored to your child’s needs. With advanced diagnostics and coordinated expertise, we bring clarity and confidence to care—so your child can start feeling better, faster.

• 60% of children seen in Mayo Clinic Children’s Complex Care Clinic receive new, updated, or clarified diagnoses after a comprehensive evaluation.
• 80% of children experience updates to their care management plans following consultation with our team, including over 60% who see adjustments to pharmacotherapy.

State-of-the-art diagnostic tools and techniques help us pinpoint underlying conditions. We integrate advanced imaging technologies, genetic testing, and biomarker analyses to gain a comprehensive understanding of each child’s condition. This thorough approach enables us to establish accurate diagnoses and formulate tailored treatment plans.

At Mayo Clinic Children’s, every child benefits from the full power of Mayo Clinic’s world-renowned research and innovation. From advanced therapies to minimally invasive procedures, we offer treatment options few others can—often developed through the very research happening within our walls. Because at Mayo Clinic, discovery and care go hand-in-hand—so your child has access to the latest proven breakthroughs. 

Behind every successful outcome is a team that works as one.

Whether your child needs a single specialist or care across multiple pediatric disciplines, our integrated teams collaborate closely to build the most effective care plan—while keeping your child at the center of every decision. With over 300 physicians across 70 pediatric specialties, you're never navigate alone.

We offer a tightly coordinated schedule that allows children to see multiple specialists within a condensed timeframe. This streamlined approach helps expedite the diagnostic process and the development of a treatment plan, enabling your family to quickly move forward and focus on what matters most — returning to home and your everyday lives.  

Child Life specialists support your child’s emotional well-being through play, preparation, and age-appropriate education. We help kids understand what to expect, reduce fear, and create a more kid-friendly experience. Whether it's a single procedure or a longer stay, we bring comfort, uplifting moments, and guidance to help families navigate their journey with confidence.

• Ranked among the nation’s top children’s hospitals
• No. 1 in the 5-state region of Minnesota, Wisconsin, Iowa, North Dakota and South Dakota for pediatric care (U.S. News & World Report)
• Designated Level 1 Children’s Surgery Center
• Home to some of the world’s top pediatric specialists

Families come to us from across the country—and the world—for care they can’t find anywhere else. 

Mayo Clinic in Minnesota

200 First St. SW, 

Rochester, MN 55905

507-738-9450

Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy below.

Terms and Conditions

Privacy Policy

Notice of Privacy Practices

Notice of Nondiscrimination

A single copy of these materials may be reprinted for noncommercial personal use only. “Mayo,” “Mayo Clinic,” “MayoClinic.org,” “Mayo Clinic Healthy Living,” and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

© 1998-2025 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved.